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The Trend-in-trend Research Design for Causal Inference
Cohort studies can be biased by unmeasured confounding. We propose a hybrid ecologic-epidemiologic design called the trend-in-trend design, which requires a strong time trend in exposure, but is unbiased unless there are unmeasured factors affecting outcome for which there are time trends in prevalence that are correlated with time trends in exposure across strata with different exposure trends...
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ژورنال
عنوان ژورنال: Bitácora Urbano Territorial
سال: 2017
ISSN: 2027-145X,0124-7913
DOI: 10.15446/bitacora.v27n4esp.63543